Compound Targets

curl -X POST https://win.oneshotagent.com/v1/tools/lookup/compound-targets \
  -H "Content-Type: application/json" \
  -H "payment-signature: <base64 x402 payment>" \
  -d '{
    "chembl_id": "CHEMBL1201580"
  }'

const response = await fetch("https://win.oneshotagent.com/v1/tools/lookup/compound-targets", {
  method: "POST",
  headers: {
    "Content-Type": "application/json",
    "payment-signature": paymentProof,
  },
  body: JSON.stringify({
    "chembl_id": "CHEMBL1201580"
  }),
});

const result = await agent.tool('lookup/compound-targets', {
  chembl_id: 'CHEMBL1201580'
});
console.log(result.result);
console.log(result.evidence);

{
  "success": true,
  "data": {
    "request_id": "uuid",
    "receipt_id": "rcpt_...",
    "status": "completed",
    "tool": "compound_targets",
    "result": {
      "matched": true,
      "candidates": [],
      "chembl_id": "CHEMBL1201580",
      "name": "ADALIMUMAB",
      "drug_type": "Antibody",
      "max_clinical_stage": "APPROVAL",
      "action_types": [
        "INHIBITOR"
      ],
      "target_types": [
        "single protein"
      ],
      "mechanisms": [
        {
          "mechanism": "TNF-alpha inhibitor",
          "action_type": "INHIBITOR",
          "target_name": "Tumor necrosis factor",
          "targets": [
            {
              "ensembl_gene_id": "ENSG00000232810",
              "symbol": "TNF"
            }
          ],
          "references": [
            {
              "source": "DailyMed",
              "urls": [
                "http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=608d4f0d-b19f-46d3-749a-7159aa5f933d"
              ]
            }
          ]
        }
      ]
    },
    "evidence": {
      "source": "Open Targets Platform (EMBL-EBI and partners)",
      "source_kind": "public",
      "retrieved_at": "2026-10-22T12:00:00.000Z",
      "calls": [
        {
          "retrieved_at": "2026-10-22T12:00:00.000Z"
        }
      ],
      "as_of": null
    }
  }
}

POST

tools

lookup

compound-targets

curl -X POST https://win.oneshotagent.com/v1/tools/lookup/compound-targets \
  -H "Content-Type: application/json" \
  -H "payment-signature: <base64 x402 payment>" \
  -d '{
    "chembl_id": "CHEMBL1201580"
  }'

const response = await fetch("https://win.oneshotagent.com/v1/tools/lookup/compound-targets", {
  method: "POST",
  headers: {
    "Content-Type": "application/json",
    "payment-signature": paymentProof,
  },
  body: JSON.stringify({
    "chembl_id": "CHEMBL1201580"
  }),
});

const result = await agent.tool('lookup/compound-targets', {
  chembl_id: 'CHEMBL1201580'
});
console.log(result.result);
console.log(result.evidence);

{
  "success": true,
  "data": {
    "request_id": "uuid",
    "receipt_id": "rcpt_...",
    "status": "completed",
    "tool": "compound_targets",
    "result": {
      "matched": true,
      "candidates": [],
      "chembl_id": "CHEMBL1201580",
      "name": "ADALIMUMAB",
      "drug_type": "Antibody",
      "max_clinical_stage": "APPROVAL",
      "action_types": [
        "INHIBITOR"
      ],
      "target_types": [
        "single protein"
      ],
      "mechanisms": [
        {
          "mechanism": "TNF-alpha inhibitor",
          "action_type": "INHIBITOR",
          "target_name": "Tumor necrosis factor",
          "targets": [
            {
              "ensembl_gene_id": "ENSG00000232810",
              "symbol": "TNF"
            }
          ],
          "references": [
            {
              "source": "DailyMed",
              "urls": [
                "http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=608d4f0d-b19f-46d3-749a-7159aa5f933d"
              ]
            }
          ]
        }
      ]
    },
    "evidence": {
      "source": "Open Targets Platform (EMBL-EBI and partners)",
      "source_kind": "public",
      "retrieved_at": "2026-10-22T12:00:00.000Z",
      "calls": [
        {
          "retrieved_at": "2026-10-22T12:00:00.000Z"
        }
      ],
      "as_of": null
    }
  }
}

Reports what the Open Targets Platform public database says about a drug or clinical candidate’s protein targets and mechanisms of action, with gene symbols and references. For research; not medical advice. Give exactly one of chembl_id or name. A PubChem CID is not accepted: pass the compound’s name, which Compound Resolve and Compound Properties return. A name search selects the first hit and lists up to three candidates so you can retry by ChEMBL id. An unknown compound returns matched: false. Does not return indications, adverse events, warnings, measured bioactivity or synthesis and preparation data.

Authentication

Requires x402 payment in the payment-signature header.

Request Body

string

ChEMBL molecule identifier; lowercase is accepted. CHEMBL followed by 1 to 9 digits, without a leading zero.

string

Drug or compound name; the first search hit is used. 2 to 100 characters.

Response (200 OK)

Top-level envelope: success (boolean) and data (object). All fields below are nested under data.

string

Durable job ID for audit and lookup

string

Job status: completed

string

Always compound_targets

object

The answer, described under Result below

object

Where the answer came from and when

string

The public body the data comes from. Always Open Targets Platform (EMBL-EBI and partners).

string

public when the data comes from a public body, commercial otherwise

string

When the lookup was made, as an ISO 8601 UTC time

string

When the source says the fact was last updated, or null when the source gives no date

Result

Nested under data.result.

boolean

Matched.

object[]

Candidates.

string

Chembl id.

string

Name.

string

Chembl id. null when the source gives no value.

string

Name. null when the source gives no value.

string

Drug type. null when the source gives no value.

string

Max clinical stage. null when the source gives no value.

string[]

Action types.

string[]

Target types.

object[]

Mechanisms.

string

Mechanism. null when the source gives no value.

string

Action type. null when the source gives no value.

string

Target name. null when the source gives no value.

object[]

Targets.

string

Ensembl gene id.

string

Symbol. null when the source gives no value.

object[]

References.

string

Source. null when the source gives no value.

string[]

Urls.

curl -X POST https://win.oneshotagent.com/v1/tools/lookup/compound-targets \
  -H "Content-Type: application/json" \
  -H "payment-signature: <base64 x402 payment>" \
  -d '{
    "chembl_id": "CHEMBL1201580"
  }'

const response = await fetch("https://win.oneshotagent.com/v1/tools/lookup/compound-targets", {
  method: "POST",
  headers: {
    "Content-Type": "application/json",
    "payment-signature": paymentProof,
  },
  body: JSON.stringify({
    "chembl_id": "CHEMBL1201580"
  }),
});

const result = await agent.tool('lookup/compound-targets', {
  chembl_id: 'CHEMBL1201580'
});
console.log(result.result);
console.log(result.evidence);

{
  "success": true,
  "data": {
    "request_id": "uuid",
    "receipt_id": "rcpt_...",
    "status": "completed",
    "tool": "compound_targets",
    "result": {
      "matched": true,
      "candidates": [],
      "chembl_id": "CHEMBL1201580",
      "name": "ADALIMUMAB",
      "drug_type": "Antibody",
      "max_clinical_stage": "APPROVAL",
      "action_types": [
        "INHIBITOR"
      ],
      "target_types": [
        "single protein"
      ],
      "mechanisms": [
        {
          "mechanism": "TNF-alpha inhibitor",
          "action_type": "INHIBITOR",
          "target_name": "Tumor necrosis factor",
          "targets": [
            {
              "ensembl_gene_id": "ENSG00000232810",
              "symbol": "TNF"
            }
          ],
          "references": [
            {
              "source": "DailyMed",
              "urls": [
                "http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=608d4f0d-b19f-46d3-749a-7159aa5f933d"
              ]
            }
          ]
        }
      ]
    },
    "evidence": {
      "source": "Open Targets Platform (EMBL-EBI and partners)",
      "source_kind": "public",
      "retrieved_at": "2026-10-22T12:00:00.000Z",
      "calls": [
        {
          "retrieved_at": "2026-10-22T12:00:00.000Z"
        }
      ],
      "as_of": null
    }
  }
}

See Pricing for this tool’s price. A wallet (x402) call receives it in the 402 quote before anything is charged; a call paid from prepaid credits is charged when the API accepts the request and answers 200.

Notes

Results return inline. The finished job stays available at /v1/requests/{request_id}

Overview

Compute

Data

Monitoring

Research & Enrich

Messaging

Web & Browser

Build

Commerce

Account & billing

Other

Compound Targets

Authentication

Request Body

Response (200 OK)

Result

Notes

​Authentication

​Request Body

​Response (200 OK)

​Result

​Notes

Authentication

Request Body

Response (200 OK)

Result

Notes